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Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT.

Identifieur interne : 000252 ( Main/Exploration ); précédent : 000251; suivant : 000253

Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT.

Auteurs : Harrison X. Bai ; Ben Hsieh ; Zeng Xiong ; Kasey Halsey ; Ji Whae Choi ; Thi My Linh Tran ; Ian Pan ; Lin-Bo Shi ; Dong-Cui Wang ; Ji Mei ; Xiao-Long Jiang ; Qiu-Hua Zeng ; Thomas K. Egglin ; Ping-Feng Hu ; Saurabh Agarwal ; Fangfang Xie ; Sha Li ; Terrance Healey ; Michael K. Atalay ; Wei-Hua Liao

Source :

RBID : pubmed:32155105

Abstract

Background Despite its high sensitivity in diagnosing COVID-19 in a screening population, chest CT appearances of COVID 19 pneumonia are thought to be non-specific. Purpose To assess the performance of United States (U.S.) and Chinese radiologists in differentiating COVID-19 from viral pneumonia on chest CT. Methods A total of 219 patients with both positive COVID-19 by RT-PCR and abnormal chest CT findings were retrospectively identified from 7 Chinese hospitals in Hunan Providence, China from January 6 to February 20, 2020. A total of 205 patients with positive Respiratory Pathogen Panel for viral pneumonia and CT findings consistent with or highly suspicious for pneumonia by original radiology interpretation within 7 days of each other were identified from Rhode Island Hospital in Providence, RI. Three Chinese radiologists blindly reviewed all chest CTs (n=424) to differentiate COVID-19 from viral pneumonia. A sample of 58 age-matched cases was randomly selected and evaluated by 4 U.S. radiologists in a similar fashion. Different CT features were recorded and compared between the two groups. Results For all chest CTs, three Chinese radiologists correctly differentiated COVID-19 from non-COVID-19 pneumonia 83% (350/424), 80% (338/424), and 60% (255/424) of the time, respectively. The seven radiologists had sensitivities of 80%, 67%, 97%, 93%, 83%, 73% and 70% and specificities of 100%, 93%, 7%, 100%, 93%, 93%, 100%. Compared to non-COVID-19 pneumonia, COVID-19 pneumonia was more likely to have a peripheral distribution (80% vs. 57%, p<0.001), ground-glass opacity (91% vs. 68%, p<0.001), fine reticular opacity (56% vs. 22%, p<0.001), and vascular thickening (59% vs. 22%, p<0.001), but less likely to have a central+peripheral distribution (14.% vs. 35%, p<0.001), pleural effusion (4.1 vs. 39%, p<0.001) and lymphadenopathy (2.7% vs. 10.2%, p<0.001). Conclusion Radiologists in China and the United States distinguished COVID-19 from viral pneumonia on chest CT with high specificity but moderate sensitivity. A translation of this abstract in Farsi is available in the supplement. - ترجمه چکیده این مقاله به فارسی، در ضمیمه موجود است.

DOI: 10.1148/radiol.2020200823
PubMed: 32155105


Affiliations:


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<name sortKey="Bai, Harrison X" sort="Bai, Harrison X" uniqKey="Bai H" first="Harrison X" last="Bai">Harrison X. Bai</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
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<name sortKey="Hsieh, Ben" sort="Hsieh, Ben" uniqKey="Hsieh B" first="Ben" last="Hsieh">Ben Hsieh</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
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<name sortKey="Xiong, Zeng" sort="Xiong, Zeng" uniqKey="Xiong Z" first="Zeng" last="Xiong">Zeng Xiong</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
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<name sortKey="Halsey, Kasey" sort="Halsey, Kasey" uniqKey="Halsey K" first="Kasey" last="Halsey">Kasey Halsey</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
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<name sortKey="Choi, Ji Whae" sort="Choi, Ji Whae" uniqKey="Choi J" first="Ji Whae" last="Choi">Ji Whae Choi</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
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<author>
<name sortKey="Tran, Thi My Linh" sort="Tran, Thi My Linh" uniqKey="Tran T" first="Thi My Linh" last="Tran">Thi My Linh Tran</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Pan, Ian" sort="Pan, Ian" uniqKey="Pan I" first="Ian" last="Pan">Ian Pan</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Shi, Lin Bo" sort="Shi, Lin Bo" uniqKey="Shi L" first="Lin-Bo" last="Shi">Lin-Bo Shi</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Wang, Dong Cui" sort="Wang, Dong Cui" uniqKey="Wang D" first="Dong-Cui" last="Wang">Dong-Cui Wang</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Mei, Ji" sort="Mei, Ji" uniqKey="Mei J" first="Ji" last="Mei">Ji Mei</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Jiang, Xiao Long" sort="Jiang, Xiao Long" uniqKey="Jiang X" first="Xiao-Long" last="Jiang">Xiao-Long Jiang</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Zeng, Qiu Hua" sort="Zeng, Qiu Hua" uniqKey="Zeng Q" first="Qiu-Hua" last="Zeng">Qiu-Hua Zeng</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Egglin, Thomas K" sort="Egglin, Thomas K" uniqKey="Egglin T" first="Thomas K" last="Egglin">Thomas K. Egglin</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Hu, Ping Feng" sort="Hu, Ping Feng" uniqKey="Hu P" first="Ping-Feng" last="Hu">Ping-Feng Hu</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Agarwal, Saurabh" sort="Agarwal, Saurabh" uniqKey="Agarwal S" first="Saurabh" last="Agarwal">Saurabh Agarwal</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Xie, Fangfang" sort="Xie, Fangfang" uniqKey="Xie F" first="Fangfang" last="Xie">Fangfang Xie</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Li, Sha" sort="Li, Sha" uniqKey="Li S" first="Sha" last="Li">Sha Li</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Healey, Terrance" sort="Healey, Terrance" uniqKey="Healey T" first="Terrance" last="Healey">Terrance Healey</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Atalay, Michael K" sort="Atalay, Michael K" uniqKey="Atalay M" first="Michael K" last="Atalay">Michael K. Atalay</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Liao, Wei Hua" sort="Liao, Wei Hua" uniqKey="Liao W" first="Wei-Hua" last="Liao">Wei-Hua Liao</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32155105</idno>
<idno type="pmid">32155105</idno>
<idno type="doi">10.1148/radiol.2020200823</idno>
<idno type="wicri:Area/PubMed/Corpus">000148</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000148</idno>
<idno type="wicri:Area/PubMed/Curation">000148</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000148</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000233</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000233</idno>
<idno type="wicri:Area/Ncbi/Merge">000C71</idno>
<idno type="wicri:Area/Ncbi/Curation">000C71</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000C71</idno>
<idno type="wicri:Area/Main/Merge">000254</idno>
<idno type="wicri:Area/Main/Curation">000252</idno>
<idno type="wicri:Area/Main/Exploration">000252</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en">Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT.</title>
<author>
<name sortKey="Bai, Harrison X" sort="Bai, Harrison X" uniqKey="Bai H" first="Harrison X" last="Bai">Harrison X. Bai</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Hsieh, Ben" sort="Hsieh, Ben" uniqKey="Hsieh B" first="Ben" last="Hsieh">Ben Hsieh</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Xiong, Zeng" sort="Xiong, Zeng" uniqKey="Xiong Z" first="Zeng" last="Xiong">Zeng Xiong</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Halsey, Kasey" sort="Halsey, Kasey" uniqKey="Halsey K" first="Kasey" last="Halsey">Kasey Halsey</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Choi, Ji Whae" sort="Choi, Ji Whae" uniqKey="Choi J" first="Ji Whae" last="Choi">Ji Whae Choi</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Tran, Thi My Linh" sort="Tran, Thi My Linh" uniqKey="Tran T" first="Thi My Linh" last="Tran">Thi My Linh Tran</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Pan, Ian" sort="Pan, Ian" uniqKey="Pan I" first="Ian" last="Pan">Ian Pan</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Shi, Lin Bo" sort="Shi, Lin Bo" uniqKey="Shi L" first="Lin-Bo" last="Shi">Lin-Bo Shi</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Wang, Dong Cui" sort="Wang, Dong Cui" uniqKey="Wang D" first="Dong-Cui" last="Wang">Dong-Cui Wang</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Mei, Ji" sort="Mei, Ji" uniqKey="Mei J" first="Ji" last="Mei">Ji Mei</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Jiang, Xiao Long" sort="Jiang, Xiao Long" uniqKey="Jiang X" first="Xiao-Long" last="Jiang">Xiao-Long Jiang</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Zeng, Qiu Hua" sort="Zeng, Qiu Hua" uniqKey="Zeng Q" first="Qiu-Hua" last="Zeng">Qiu-Hua Zeng</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Egglin, Thomas K" sort="Egglin, Thomas K" uniqKey="Egglin T" first="Thomas K" last="Egglin">Thomas K. Egglin</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Hu, Ping Feng" sort="Hu, Ping Feng" uniqKey="Hu P" first="Ping-Feng" last="Hu">Ping-Feng Hu</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Agarwal, Saurabh" sort="Agarwal, Saurabh" uniqKey="Agarwal S" first="Saurabh" last="Agarwal">Saurabh Agarwal</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Xie, Fangfang" sort="Xie, Fangfang" uniqKey="Xie F" first="Fangfang" last="Xie">Fangfang Xie</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Li, Sha" sort="Li, Sha" uniqKey="Li S" first="Sha" last="Li">Sha Li</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Healey, Terrance" sort="Healey, Terrance" uniqKey="Healey T" first="Terrance" last="Healey">Terrance Healey</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Atalay, Michael K" sort="Atalay, Michael K" uniqKey="Atalay M" first="Michael K" last="Atalay">Michael K. Atalay</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Liao, Wei Hua" sort="Liao, Wei Hua" uniqKey="Liao W" first="Wei-Hua" last="Liao">Wei-Hua Liao</name>
<affiliation>
<nlm:affiliation>From the Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China 410008 (Z.X., D.C.W., F.X., S.L., W.H.L.), Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA, 02903 (H.X.B., B.H., K.H., I.P., T.K.E., S.A., T.H., M.K.A.), Brown University Warren Alpert Medical School, Providence, RI, USA 02903 (K.H., J.W.C., T.M.L.T., I.P., T.K.E.), Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA 02912 (L.B.S.), Department of Radiology, Changde Second People's Hospital, Changde, Hunan, China 415001 (J.M.), Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, Hunan, China 421002 (X.L.J.), Department of Radiology, Loudi Central Hospital, Loudi, Hunan, China 417000 (Q.H.Z.,), and Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, Hunan, China 423000 (P.F.H.).</nlm:affiliation>
<wicri:noCountry code="subField">China 423000 (P.F.H.).</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Radiology</title>
<idno type="eISSN">1527-1315</idno>
<imprint>
<date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Background Despite its high sensitivity in diagnosing COVID-19 in a screening population, chest CT appearances of COVID 19 pneumonia are thought to be non-specific. Purpose To assess the performance of United States (U.S.) and Chinese radiologists in differentiating COVID-19 from viral pneumonia on chest CT. Methods A total of 219 patients with both positive COVID-19 by RT-PCR and abnormal chest CT findings were retrospectively identified from 7 Chinese hospitals in Hunan Providence, China from January 6 to February 20, 2020. A total of 205 patients with positive Respiratory Pathogen Panel for viral pneumonia and CT findings consistent with or highly suspicious for pneumonia by original radiology interpretation within 7 days of each other were identified from Rhode Island Hospital in Providence, RI. Three Chinese radiologists blindly reviewed all chest CTs (n=424) to differentiate COVID-19 from viral pneumonia. A sample of 58 age-matched cases was randomly selected and evaluated by 4 U.S. radiologists in a similar fashion. Different CT features were recorded and compared between the two groups. Results For all chest CTs, three Chinese radiologists correctly differentiated COVID-19 from non-COVID-19 pneumonia 83% (350/424), 80% (338/424), and 60% (255/424) of the time, respectively. The seven radiologists had sensitivities of 80%, 67%, 97%, 93%, 83%, 73% and 70% and specificities of 100%, 93%, 7%, 100%, 93%, 93%, 100%. Compared to non-COVID-19 pneumonia, COVID-19 pneumonia was more likely to have a peripheral distribution (80% vs. 57%, p<0.001), ground-glass opacity (91% vs. 68%, p<0.001), fine reticular opacity (56% vs. 22%, p<0.001), and vascular thickening (59% vs. 22%, p<0.001), but less likely to have a central+peripheral distribution (14.% vs. 35%, p<0.001), pleural effusion (4.1 vs. 39%, p<0.001) and lymphadenopathy (2.7% vs. 10.2%, p<0.001). Conclusion Radiologists in China and the United States distinguished COVID-19 from viral pneumonia on chest CT with high specificity but moderate sensitivity.
<i>A translation of this abstract in Farsi is available in the supplement.</i>
- ترجمه چکیده این مقاله به فارسی، در ضمیمه موجود است.</div>
</front>
</TEI>
<affiliations>
<list></list>
<tree>
<noCountry>
<name sortKey="Agarwal, Saurabh" sort="Agarwal, Saurabh" uniqKey="Agarwal S" first="Saurabh" last="Agarwal">Saurabh Agarwal</name>
<name sortKey="Atalay, Michael K" sort="Atalay, Michael K" uniqKey="Atalay M" first="Michael K" last="Atalay">Michael K. Atalay</name>
<name sortKey="Bai, Harrison X" sort="Bai, Harrison X" uniqKey="Bai H" first="Harrison X" last="Bai">Harrison X. Bai</name>
<name sortKey="Choi, Ji Whae" sort="Choi, Ji Whae" uniqKey="Choi J" first="Ji Whae" last="Choi">Ji Whae Choi</name>
<name sortKey="Egglin, Thomas K" sort="Egglin, Thomas K" uniqKey="Egglin T" first="Thomas K" last="Egglin">Thomas K. Egglin</name>
<name sortKey="Halsey, Kasey" sort="Halsey, Kasey" uniqKey="Halsey K" first="Kasey" last="Halsey">Kasey Halsey</name>
<name sortKey="Healey, Terrance" sort="Healey, Terrance" uniqKey="Healey T" first="Terrance" last="Healey">Terrance Healey</name>
<name sortKey="Hsieh, Ben" sort="Hsieh, Ben" uniqKey="Hsieh B" first="Ben" last="Hsieh">Ben Hsieh</name>
<name sortKey="Hu, Ping Feng" sort="Hu, Ping Feng" uniqKey="Hu P" first="Ping-Feng" last="Hu">Ping-Feng Hu</name>
<name sortKey="Jiang, Xiao Long" sort="Jiang, Xiao Long" uniqKey="Jiang X" first="Xiao-Long" last="Jiang">Xiao-Long Jiang</name>
<name sortKey="Li, Sha" sort="Li, Sha" uniqKey="Li S" first="Sha" last="Li">Sha Li</name>
<name sortKey="Liao, Wei Hua" sort="Liao, Wei Hua" uniqKey="Liao W" first="Wei-Hua" last="Liao">Wei-Hua Liao</name>
<name sortKey="Mei, Ji" sort="Mei, Ji" uniqKey="Mei J" first="Ji" last="Mei">Ji Mei</name>
<name sortKey="Pan, Ian" sort="Pan, Ian" uniqKey="Pan I" first="Ian" last="Pan">Ian Pan</name>
<name sortKey="Shi, Lin Bo" sort="Shi, Lin Bo" uniqKey="Shi L" first="Lin-Bo" last="Shi">Lin-Bo Shi</name>
<name sortKey="Tran, Thi My Linh" sort="Tran, Thi My Linh" uniqKey="Tran T" first="Thi My Linh" last="Tran">Thi My Linh Tran</name>
<name sortKey="Wang, Dong Cui" sort="Wang, Dong Cui" uniqKey="Wang D" first="Dong-Cui" last="Wang">Dong-Cui Wang</name>
<name sortKey="Xie, Fangfang" sort="Xie, Fangfang" uniqKey="Xie F" first="Fangfang" last="Xie">Fangfang Xie</name>
<name sortKey="Xiong, Zeng" sort="Xiong, Zeng" uniqKey="Xiong Z" first="Zeng" last="Xiong">Zeng Xiong</name>
<name sortKey="Zeng, Qiu Hua" sort="Zeng, Qiu Hua" uniqKey="Zeng Q" first="Qiu-Hua" last="Zeng">Qiu-Hua Zeng</name>
</noCountry>
</tree>
</affiliations>
</record>

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